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# Christopher Lane Trust

Helping you get diagnosed and treated for hypopituitarism

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- [When talking therapies don't work](https://christopherlanetrust.org.uk/when-talking-therapies-dont-work/) - The anniversary of Chris’s death was last Bank Holiday Monday. He has been dead for 17 years. Sometimes I think I’ve got over it. Sometimes I don’t. Recently I’ve spent time on LinkedIn, connecting with suicide groups. The prevailing suicide prevention trend is to encourage people to ask their friends if they are all right,
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- [The Test That Doesn't Test](https://christopherlanetrust.org.uk/the-test-that-doesnt-test/) - A must-read for anyone who thinks they may have cortisol deficiency or GHD Once upon a time there was a Yorkshire lady named Christine Wrightson. Here she is. You can see the kind of person she was: downright, valiant, not to be messed with. She got ill. She’d had arthritis for decades and in 2005
- [The Test That Doesn't Test, Continued](https://christopherlanetrust.org.uk/the-test-that-doesnt-test-continued/) - Christine knew that she was not alone. There had to be other pituitary patients misdiagnosed like her with ME or Chronic Fatigue Syndrome. She told her story to them, ending with these words:.= “I put my heart and soul into my story. I wrote it to help you. I think of you all each and
- [The A-Z with something missing, Continued](https://christopherlanetrust.org.uk/the-a-z-with-something-missing-continued/) - Over the past month I have been asking people with growth hormone deficiency to tell their heart-wrenching stories to the NHS – about their long years of non-diagnosis and the medical scepticism about their symptoms, their suicidal feelings and attempts – and to urge that the A-Z of Health Conditions should at least contain a
- [The A-Z with something missing](https://christopherlanetrust.org.uk/the-a-z-with-something-missing/) - GHD doesn’t stand for Ghastly Horrific Disease, but it could do. It happens after a sixth of concussions, and roughly a quarter of more serious head injuries and it makes you want to kill yourself. Interestingly, suicide risk is tripled after concussion, and four times after worse injury. There were over 100,000 people admitted to
- [Maybe it's not CTE after all?](https://christopherlanetrust.org.uk/maybe-its-not-cte-after-all/) - You've had multiple concussions in sport. Do you have: Impaired concentration and memory loss? Lack of well-being? Depression and anxiety? Reduced energy? If so, you may fear you have early signs of Chronic Traumatic Encephalopathy (CTE) and that it'll be downhill all the way with this incurable condition. But maybe it's not as bad as
- [Head Injury and Suicide](https://christopherlanetrust.org.uk/head-injury-and-suicide/) - A large Danish population study which looked at more than 100,000 hospital admissions for head injury for over a decade and examined the causes of death, found this: You are four times more likely to kill yourself after you’ve suffered bruising or bleeding to the brain. You are three times more likely after concussion. You
- [A Glaring Omission](https://christopherlanetrust.org.uk/a-glaring-omission/) - On Monday 18th December 2023, the Telegraph ran an article headed WHAT CONCUSSION CAN DO TO YOU. The author listed the symptoms - headaches or dizziness, difficulty concentrating or remembering, anxiety, low mood, fatigue and difficulty sleeping - and was absolutely silent about the worst symptom of all, which is loss of libido. Shouldn't parents
- [Hidden illness](https://christopherlanetrust.org.uk/hidden-illness/) - Patrick, 49, had a plan if his test result was negative. He would swallow his blood-thinning pills and some diazepam, then run a hot bath, get in, and slice into his femoral artery. The blood-thinners would prevent clotting. “It wouldn’t have been a cry for help. I didn’t intend to fail,” he says. Luckily the
- [Shanti De Cort: Was everything checked?](https://christopherlanetrust.org.uk/shanti-de-cort-was-everything-checked/) - Last May a 23-year-old Flemish girl was granted legal euthanasia on the grounds that ‘she was in a medically futile condition of mental suffering.’ Shanti De Corte died surrounded by her family including her mother, who supported her decision. She had suffered serious psychological issues in her teens, but the real trigger was the terrorist
- [The government is digging a deeper and deeper hole each year. How long before it topples in?](https://christopherlanetrust.org.uk/the-hole/) - Yesterday I wrote to our MP, Chris Philp, as follows: May I ask what plans the government has made to meet the ever-increasing cost to the state of undiagnosed hypopituitarism patients? Now that NICE has at last undertaken to include the risk of post-traumatic hypopituitarism in its head injury guidance update in March, it seems
- [Did Sir Louis earn it?](https://christopherlanetrust.org.uk/did-sir-louis-earn-it/) - Professor Louis Appleby has received a Knighthood in the 2023 New Year’s Honours listed for his ‘services to medicine and mental health’. No doubt he is being congratulated widely. However, do his services to mental health really bear close examination? He leads the National Suicide Prevention Strategy for England. Such a strategy is vital to
- [“Talking therapies don’t always work” says Kate](https://christopherlanetrust.org.uk/talking-therapies-dont-always-work-says-kate/) - Whether the Princess was obliquely referring to her brother-in-law last week we shall never know, but one person endorses her comment wholeheartedly. John Willsher (not his real name) aged 51, a likeable and articulate clarinet player from south London, would argue strongly against the received wisdom that more men kill themselves than women because they

## Pages

- [Home](https://christopherlanetrust.org.uk/)
- [Purchase Paperback Book](https://christopherlanetrust.org.uk/purchase-paperback-book/) - To place your order of ‘Mother of a Suicide’ for only £10, please complete the form and we will contact you.
- [Media](https://christopherlanetrust.org.uk/media/) - Media Publications 2025 Letters to the Editor, Sunday Times, 20 April 2025 DailyMail – GoodHealth – ConcussionSymptoms 2023 2022 Brown Book, Lady Margaret Hall, Oxford 2021 2020 2019 2017 2016 2014 2013 2012 2011 2010 2009
- [About Us](https://christopherlanetrust.org.uk/about-us/) - The Christopher Lane Trust is dedicated to Christopher Lane who took his own life in 2008 at the age of 31. The Trust seeks to help anyone who believes they may have hypopituitarism and have difficulty getting the right tests. What is hypopituitarism?Hypopituitarism is damage to the pituitary gland, often caused by a head injury,
- [Personal Stories](https://christopherlanetrust.org.uk/personal-stories/) - Here are some stories from people who had a head injury which caused later pituitary deficiencies, including the two most frequent problems – hypogonadism (which can cause erectile dysfunction / impotence, loss of libido, loss of periods, infertility) and growth hormone deficiency, which can interfere with growth in children, and can cause muscle loss and
- [Case Study D - Saved by hormone replacement](https://christopherlanetrust.org.uk/personal-stories/case-study-d-saved-by-hormone-replacement/) - James Smith – account published in BMJ’s Rapid Responses After being badly beaten up in a street robbery six years ago and nearly losing an eye, I suffered severe depression and tried to kill myself several times. I did not know then that a large Danish epidemiological study had found that the risk of suicide
- [Case Study C - Falling off a bed](https://christopherlanetrust.org.uk/personal-stories/case-study-c-falling-off-a-bed/) - Study in Endocrine 2007 “Vera”, aged 26 went to the doctors complaining of severe weight gain, swollen ankles, weakness, mild headache and high blood pressure, and was given a thorough hormone check. She’d had a history of problems. At the age of seven she had been diagnosed with diabetes insipidus (a condition that means passing
- [Case Study B - Playing soccer](https://christopherlanetrust.org.uk/personal-stories/case-study-b-playing-soccer/) - Study in Journal of Athletic Training (2007) “Gary” was a promising junior soccer player who was the youngest in his team and spent his weekends travelling to inter-school matches. But between ages 14 to 16 he stopped growing, remaining at 5ft 6in. This was strange because his father was nearly 6 feet and both his
- [Case Study A - A car crash and a fall](https://christopherlanetrust.org.uk/personal-stories/case-study-a-a-car-crash-and-a-fall/) - Study in Endocrine Abstracts (2007) ‘Greg’ aged 21, was hit by a car going at 50 mph. While he was in intensive care he was producing too much urine. This can be a sign that the pituitary gland has been damaged, so the doctors tested his other hormones too, and found that he was very
- [Kenneth Starr](https://christopherlanetrust.org.uk/personal-stories/kenneth-starr/) - I was born in 1943 and grew up in Northern Ireland. In my youth I enjoyed playing hockey and tennis. I played these too at teacher training college in Manchester and later at senior level in Africa and in England. Even at that stage, I had some stamina and fatigue problems, and depression. Then I
- [Robert Francis Hunter](https://christopherlanetrust.org.uk/personal-stories/robert-francis-hunter/) - Dated 5 January 2021 I had a good up-bringing but my dad developed a mental health problem and lost his job when I was very young. It was a shame as he was a Technician Electrical Engineer and made good money. My mother was a clerical short-hand typist. My two brothers have good jobs: one
- [Katie Hughes](https://christopherlanetrust.org.uk/personal-stories/katie-hughes/) - Excerpt from ‘Mother of a Suicide’ by Joanna Lane The very worst thing was the not knowing. There were things that I did know: that I wasn’t well; that I was experiencing fluctuating, seemingly unconnected symptoms; that I was unable to persuade any doctor bar my GP to listen to me; that I wasn’t believed
- [Jill Mizen](https://christopherlanetrust.org.uk/personal-stories/jill-mizen/) - See BMJ Rapid Responses http://www.bmj.com/content/346/bmj.f894/rr/643479 Jill did not have a head injury, but her experience of having a normal result for the short synacthen test and then being told she had chronic fatigue syndrome has important implications for head injury survivors. I lost a lot of blood during my first pregnancy and had raised blood
- [Alice](https://christopherlanetrust.org.uk/personal-stories/alice/) - With thanks to Pituitary Life July 2011I was first diagnosed with cranial diabetes insipidus (CDI) in 1997; my symptoms began a year prior to my diagnosis. I have a pituitary tumour, which has caused the condition – one possible reason for the tumour could be a head trauma that I sustained around the age of
- [Byron](https://christopherlanetrust.org.uk/personal-stories/byron/) - By his motherA case of hypopituitarism caused not by head injury but by neurosurgery At 8 years old Byron had two episodes of neurosurgery 6 months apart. The first was pretty straightforward but the second was not so smooth and post-surgical complication and a low GCS score made for a very slow recovery. None the
- [Jon](https://christopherlanetrust.org.uk/personal-stories/jon/) - I have a Pituitary Neoplasia and I had a head injury at the age of four. My cousin picked me up, flung me over her shoulder, and lost her grip on my legs. I slid, face first, down her back and landed on my forehead on concrete. It drove my head backward, toward my tailbone,
- [Bev](https://christopherlanetrust.org.uk/personal-stories/bev/) - Bev had a head injury and suffered pituitary problems later in life. She gives her moving story here. Her head injury may not have caused her hormone problems: so far there is no research supporting a connection between head injury and prolactinoma. However her story is important and may strike a chord with some readers.
- [Michele](https://christopherlanetrust.org.uk/personal-stories/michele/) - Michele had a head injury and suffered pituitary problems later in life. She gives her moving story here. Her head injury may not have caused her hormone problems: so far there is no research supporting a connection between head injury and acromegaly. However her story is important and may strike a chord with some readers.
- [Linda](https://christopherlanetrust.org.uk/personal-stories/linda/) - Linda had a head injury and suffered pituitary problems later in life. She gives her moving story here. Her head injury may not have caused her hormone problems: so far there is no research supporting a connection between head injury and prolactinoma. However her story is important and may strike a chord with some readers.
- [Hayley](https://christopherlanetrust.org.uk/personal-stories/hayley/) - Her mum’s friend writes: Hayley has been a champion ice skater since the time she was a young child (she is almost 18 yrs old). About three years ago, Hayley had a very bad fall on the ice. She suffered a severe concussion and had to stay home from school for almost 6 months. Her
- [Ashley](https://christopherlanetrust.org.uk/personal-stories/ashley/) - Your son’s story mirrors my own life. I apparently had a head injury in 1972, aged 8 or 9 about which I was not told until approx 1993. I think this probably explains why I don’t have memories before age 9 (which makes life difficult enough) though my memory is now efficient. A few years
- [Robin](https://christopherlanetrust.org.uk/personal-stories/robin/) - I had a head injury at the age of 7, like your son. I can relate to a lot of the problems that he had. I only became aware myself that something was wrong two years ago – 28 years after the accident. However I did suffer from problems throughout this time but they were
- [Rashid](https://christopherlanetrust.org.uk/personal-stories/rashid/) - I fell down from a one story building and rolled down another story on cement steps at age 7. I am 55 years old now and have a normal growth but since childhood had sexual problems. I have very small testicles and even now my Hormone level is 224. I have read that childhood head
- [Kenneth](https://christopherlanetrust.org.uk/personal-stories/kenneth/) - I was attacked by a gang in N Z a couple of years ago. I sustained brain damage to three areas of the brain, including the frontal lobe. I have been doing some research work with Imperial Medical College. It appears I have damaged my pituitary gland. I am waiting on the results of their
- [A 34 year old man who responded through the website](https://christopherlanetrust.org.uk/personal-stories/a-34-year-old-man-who-responded-through-the-website/) - I can sympathise with your son and can totally understand why he did what he did, its so hard trying to keep it all together sometimes. I have been in some very low places these last few years too and its hard to carry on sometimes, you just want to be normal again! I am
- [Eddie Barker](https://christopherlanetrust.org.uk/personal-stories/eddie-barker/) - (See BMJ rapid responses) I had three head injuries between 1972 and 2003: an accident when I was driving a truck in 1972, a violent assault in 1985 when I had a basal skull fracture, and the third head injury in 2003. After this I began to suffer from right neck pain from spondylosis, dizziness
- [James Smith](https://christopherlanetrust.org.uk/personal-stories/james-smith/) - Broadcasted on Radio Solent 20 March 2012Excerpt from Radio Solent programme aired 20 March 2012, telling James Smith’s story Dominic Blake: That’s right Julian, I’m afraid it’s the stuff of nightmares, James was a successful executive, quite a high flier, but on a night out in 2007 his life as he knew it pretty much
- [Treatment](https://christopherlanetrust.org.uk/treatment/) - Growth Hormone Deficiency (GHD)Cortisol DeficiencySex Hormone DeficiencyThyroid Hormone DeficiencyArginine Vasopressin Deficiency (AVD)Prolactin Abnormality Treatment for Growth Hormone Deficiency (GHD) Click here to view Diagnosis of Growth Hormone Deficiency If any of your other pituitary hormones are lacking, your endocrinologist must treat these first, and only start GH treatment when these other hormones are at the
- [Symptoms](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/) - Do you have any of these Symptoms? Each of the following symptoms can be caused by failure of your pituitary gland. Select a symptom from the list below to see which hormone/s could be deficient. If you have these symptoms (not necessarily all of them), they could be caused by failure of your pituitary gland.Read
- [Diagnosis](https://christopherlanetrust.org.uk/diagnosis/) - Growth Hormone Deficiency (GHD)Cortisol DeficiencySex Hormone DeficiencyThyroid Hormone DeficiencyArginine Vasopressin Deficiency (AVD)Prolactin Abnormality4 Mistaken ReasonsDiagnosis Statistics Diagnosis of Growth Hormone Deficiency (GHD) Click here to view Treatment for Growth Hormone Deficiency Tests Insulin tolerance test (aka insulin stress test) or glucagon stimulation test or GHRH arginine test or Macimorelin test (not yet widely available) These
- [Information Leaflets](https://christopherlanetrust.org.uk/about-us/information-leaflets/) - Information Leaflets Christopher_Lane_Trust_Parliamentary_Leaflet Christopher_Lane_Trust_Sports_Leaflet IMG_8557 Information Leaflet – Depression Previous Next
- [Causes](https://christopherlanetrust.org.uk/causes/) - CausesMajor Cause (Head Injury) Head injury (major cause) – Read More • Brain surgery• Radiation treatment to the head or neck• Lack of blood flow to the brain or pituitary gland (stroke) or bleeding (hemorrhage) into the brain or pituitary gland• Certain medications, such as narcotics, high-dose corticosteroids such as prednisone, or certain cancer drugs
- [Fatigue / Low Energy](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/fatigue-low-energy/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Cortisol DeficiencyThyroid Hormone DeficiencyArginine Vasopressin Deficiency (AVD) Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the
- [Weight Loss](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/weight-loss/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Cortisol Deficiency Cortisol Deficiency The most common symptoms of cortisol deficiency* are chronic, or long-lasting, fatigue muscle weakness loss of appetite weight loss abdominal pain Other symptoms can
- [Weight Gain](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/weight-gain/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Thyroid Hormone Deficiency Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in muscle
- [Urination More Frequent and Thirst](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/urination-more-frequent-and-thirst/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Arginine Vasopressin Deficiency (AVD) Arginine Vasopressin Deficiency (AVD) The symptoms of AVD are Increased thirst Frequent urination Increased urine volume Pale or colorless, watery urine Night-time urination (nocturia)
- [Temperature Regulation (Increased Sensitivity to Cold or Heat)](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/temperature-regulation-increased-sensitivity-to-cold-or-heat/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Thyroid Hormone Deficiency Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in muscle
- [Suicidal Thoughts](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/suicidal-thoughts/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Cortisol DeficiencySex Hormone DeficiencyThyroid Hormone Deficiency Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist)
- [Sex Drive Reduced](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/sex-drive-reduced/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Cortisol DeficiencySex Hormone DeficiencyThyroid Hormone DeficiencyProlactin Abnormality Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the
- [Periods (Irregular or None)](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/periods-irregular-or-none/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Cortisol DeficiencySex Hormone DeficiencyThyroid Hormone DeficiencyProlactin Abnormality Cortisol Deficiency The most common symptoms of cortisol deficiency* are chronic, or long-lasting, fatigue muscle weakness loss of appetite
- [Pale Appearance](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/pale-appearance/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Thyroid Hormone Deficiency Thyroid Hormone Deficiency Symptoms of thyroid deficiency are tiredness being sensitive to cold weight gain constipation depression and anxiety slow movements and thoughts muscle aches
- [Osteoporosis](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/osteoporosis/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Sex Hormone DeficiencyProlactin Abnormality Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in
- [Muscle Weakness](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/muscle-weakness/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Sex Hormone DeficiencyThyroid Hormone DeficiencyProlactin Abnormality Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist)
- [Milky Discharge From Breasts (Males and Females)](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/milky-discharge-from-breasts-males-and-females/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Prolactin Abnormality Prolactin Abnormality Excess prolactin This is the most common prolactin abnormality. If your pituitary gland is affected, it may not produce prolactin inhibiting factors (PIFs), such
- [Man Boobs](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/man-boobs/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Prolactin Abnormality Prolactin Abnormality Excess prolactin This is the most common prolactin abnormality. If your pituitary gland is affected, it may not produce prolactin inhibiting factors (PIFs), such
- [Low Blood Pressure](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/low-blood-pressure/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Cortisol Deficiency Cortisol Deficiency The most common symptoms of cortisol deficiency* are chronic, or long-lasting, fatigue muscle weakness loss of appetite weight loss abdominal pain Other symptoms can
- [Impotence (In Men)](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/impotence-in-men/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Sex Hormone DeficiencyProlactin Abnormality Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in
- [High Blood Fats](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/high-blood-fats/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Growth Hormone Deficiency (GHD) Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in muscle less strength and stamina,
- [Heart Trouble](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/heart-trouble/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Growth Hormone Deficiency (GHD) Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in muscle less strength and stamina,
- [Headaches](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/headaches/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Cortisol DeficiencyProlactin Abnormality Cortisol Deficiency The most common symptoms of cortisol deficiency* are chronic, or long-lasting, fatigue muscle weakness loss of appetite weight loss abdominal pain
- [Fertility Reduced](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/fertility-reduced/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Cortisol DeficiencySex Hormone DeficiencyProlactin Abnormality Cortisol Deficiency The most common symptoms of cortisol deficiency* are chronic, or long-lasting, fatigue muscle weakness loss of appetite weight loss
- [Dry Skin](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/dry-skin/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Thyroid Hormone Deficiency Thyroid Hormone Deficiency Symptoms of thyroid deficiency are tiredness being sensitive to cold weight gain constipation depression and anxiety slow movements and thoughts muscle aches
- [Dizziness on Standing](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/dizziness-on-standing/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Cortisol Deficiency Cortisol Deficiency The most common symptoms of cortisol deficiency* are chronic, or long-lasting, fatigue muscle weakness loss of appetite weight loss abdominal pain Other symptoms can
- [Depression](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/depression/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Cortisol DeficiencySex Hormone DeficiencyThyroid Hormone Deficiency Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist)
- [Constipation](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/constipation/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Thyroid Hormone Deficiency Thyroid Hormone Deficiency Symptoms of thyroid deficiency are tiredness being sensitive to cold weight gain constipation depression and anxiety slow movements and thoughts muscle aches
- [Brain Fog / Memory Problems](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/brain-fog-memory-problems/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. The hormone below could be deficient. Growth Hormone Deficiency (GHD) Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in muscle less strength and stamina,
- [Body Hair Loss](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/body-hair-loss/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Sex Hormone DeficiencyThyroid Hormone DeficiencyProlactin Abnormality Sex Hormone Deficiency Your gonadotrophic hormones (LH/FSH) are what stimulate your sex organs to make testosterone and oestrogen. If they
- [Anxiety](https://christopherlanetrust.org.uk/symptoms-of-hypopituitarism/anxiety/) - Click on the plus below to select another symptom: This symptom could be caused by the failure of your pituitary gland. Below are the hormones that could be deficient. Growth Hormone Deficiency (GHD)Cortisol DeficiencySex Hormone DeficiencyThyroid Hormone DeficiencyProlactin Abnormality Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the
- [Campaign Documents](https://christopherlanetrust.org.uk/campaign-documents/) - ACQUIRED BRAIN INJURY STRATEGY RESPONSE TO CALL FOR EVIDENCE (From Christopher Lane Trust) 1. EXECUTIVE SUMMARY A significant percentage of ABI-survivors, including the concussed, suffer hormonal deficits, which can cause fatigue, impotence and infertility, brain fog, anxiety, depression, heart problems and osteoporosis. These deficits may take a while to show. Patients are not warned, and
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- [CLT Site Footer](https://christopherlanetrust.org.uk/?elementor_library=clt-site-footer) - Helping you get diagnosed and treated for hypopituitarism Donate Purchase our Book (Kindle) Purchase our Book (Paperback) Charity number: 1192336 | View Full Details News Flash Head injury makes you four times more likely to die by suicide. Read more here. © All rights reserved Twitter Made with ❤ by Montoya Marketing
- [Diagnosis Statistics - Causes](https://christopherlanetrust.org.uk/?elementor_library=diagnosis-statistics) - Statistics The following table was kindly supplied by NHSDigital in September 2016. It shows the total numbers of UK patients diagnosed annually with hypopituitarism (coded as E230) from any cause between 2007 and 2015. According to NHSDigital the figures for Out-Patient Care are less reliable than for Admitted Patient Care. Looking only at Admitted Patient
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- [Cortisol Deficiency - Diagnosis](https://christopherlanetrust.org.uk/?elementor_library=cortisol-deficiency-2) - Diagnosis of Cortisol Deficiency (aka hypoadrenalism / adrenal insufficiency) Click here to view Treatment for Cortisol Deficiency Tests Your 9am cortisol level should be checked. If it is below 500nmol/L* and you have symptoms, you need a dynamic test (also called a provocative/stimulation test): Insulin tolerance test (aka insulin stress test) – best option Glucagon
- [Growth Hormone Deficiency - Treatment](https://christopherlanetrust.org.uk/?elementor_library=growth-hormone-deficiency-2) - Diagnosis of Growth Hormone Deficiency (GHD) Click here to view Treatment for Growth Hormone Deficiency Tests Insulin tolerance test (aka insulin stress test) or glucagon stimulation test or GHRH arginine test or Macimorelin test (not yet widely available) These are all dynamic tests. Dynamic tests are the only way to test for GHD. Consultants may
- [Growth Hormone Deficiency](https://christopherlanetrust.org.uk/?elementor_library=symptoms-ghd) - Growth hormone deficiency (GHD) Growth hormone deficiency can cause: increase in body fat (especially around the waist) decrease in muscle less strength and stamina, less ability to exercise weaker bones, more fractures in middle age and beyond more LDL blood cholesterol, less HDL excessive tiredness anxiety and depression feelings of social isolation brain fog and
- [Thyroid Hormone Deficiency - Symptoms](https://christopherlanetrust.org.uk/?elementor_library=thyroid-hormone-deficiency) - Thyroid Hormone Deficiency Symptoms of thyroid deficiency are tiredness being sensitive to cold weight gain constipation depression and anxiety slow movements and thoughts muscle aches and weakness muscle cramps dry and scaly skin brittle hair and nails loss of libido (sex drive) pain, numbness and a tingling sensation in the hand and fingers (carpal tunnel syndrome)
- [Cortisol Deficiency](https://christopherlanetrust.org.uk/?elementor_library=cortisol-deficiency) - Cortisol Deficiency The most common symptoms of cortisol deficiency* are chronic, or long-lasting, fatigue muscle weakness loss of appetite weight loss abdominal pain Other symptoms can include nausea vomiting diarrhoea low blood pressure that drops further when you stand up, causing dizziness or fainting irritability, anxiety and depression joint pain craving salty foods hypoglycemia, or
- [CL Website Header Homepage](https://christopherlanetrust.org.uk/?elementor_library=elementor-header-2041) - Christopher Mark Lane, 1976 – 2008 Fatigue? Depression? Impotence? No relief from multiple symptoms? Our information could help you find out why, and get treatment. Search Symptoms
- [Prolactin Abnormality - Symptoms](https://christopherlanetrust.org.uk/?elementor_library=prolactin-abnormality) - Prolactin Abnormality Excess prolactin This is the most common prolactin abnormality. If your pituitary gland is affected, it may not produce prolactin inhibiting factors (PIFs), such as dopamine. The symptoms are In women Difficulty in getting pregnant Disruption in periods Loss of sex drive Painful sex through vaginal dryness Low bone mass Breasts producing milk
- [Arginine Vasopressin Deficiency - Symptoms](https://christopherlanetrust.org.uk/?elementor_library=arginine-vasopressin-deficiency) - Arginine Vasopressin Deficiency (AVD) The symptoms of AVD are Increased thirst Frequent urination Increased urine volume Pale or colorless, watery urine Night-time urination (nocturia) Fatigue due to frequent nighttime urination and interrupted sleep Constant thirst and urination Shauna: “For years, I have told the doctor of my intense thirst and dry mouth. I have frequent
- [Sex Hormone Deficiency - Symptoms](https://christopherlanetrust.org.uk/?elementor_library=sex-hormone-deficiency) - Sex Hormone Deficiency Your gonadotrophic hormones (LH/FSH) are what stimulate your sex organs to make testosterone and oestrogen. If they fail, the symptoms are: Erectile dysfunction Infertility Less hair growth on the face and body Less muscle Development of breast tissue (gynecomastia) Bone weakness (osteoporosis) Depression and anxiety For menIn severe cases Difficulty concentrating Hot
- [Arginine Vasopressin Deficiency - Treatment](https://christopherlanetrust.org.uk/?elementor_library=arginine-vasopressin-deficiency-3) - Treatment for Arginine Vasopressin Deficiency (AVD) (Diabetes Insipidus) Click here to view Diagnosis of Arginine Vasopressin Deficiency (AVD) If your diabetes insipidus is only mild, you will be advised to drink more water. If your condition is caused by, for example, a tumour in your pituitary or hypothalamus, you will first receive treatment for this. Then
- [Thyroid Hormone Deficiency - Treatment](https://christopherlanetrust.org.uk/?elementor_library=thyroid-hormone-deficiency-3) - Treatment for Thyroid Hormone Deficiency (Hypothyroidism) Click here to view Diagnosing Thyroid Hormone Deficiency The treatment will usually be levothyroxine tablets taken daily. Levothyroxine is a synthetic version of the thyroxine hormone. The dose will have to be adjusted to suit you, usually starting low and increasing gradually. You will have blood tests after 6-8 weeks
- [Sex Hormone Deficiency - Treatment](https://christopherlanetrust.org.uk/?elementor_library=sex-hormone-deficiency-3) - Treatment for Sex Hormone Deficiency (Secondary Hypogonadism) Click here to view Diagnosis of Sex Hormone Deficiency For males Testosterone replacement You will usually be treated with testosterone replacement to return testosterone levels to normal. You may be treated with intramuscular injections given anywhere from two to 10 weeks apart, gel, patches, pellets under the skin,
- [Cortisol Deficiency - Treatment](https://christopherlanetrust.org.uk/?elementor_library=cortisol-deficiency-3) - Treatment for Cortisol Deficiency Click here to view Diagnosis of Cortisol Deficiency Medication Your cortisol will be replaced with hydrocortisone, to be taken several times a day by mouth. You may find that careful fine-tuning of the timing and amount of your dose to imitate your body’s natural rhythms will help you, see https://www.pituitary.org.uk/support-for-you/peer-support/patient-stories/gail%E2%80%99s-story-hydrocortisone-regime/ Alternatively, less
- [Growth Hormone Deficiency - Diagnosis](https://christopherlanetrust.org.uk/?elementor_library=growth-hormone-deficiency) - Treatment for Growth Hormone Deficiency (GHD) Click here to view Diagnosis of Growth Hormone Deficiency If any of your other pituitary hormones are lacking, your endocrinologist must treat these first, and only start GH treatment when these other hormones are at the right level. Injections You will be given injection pens to inject yourself daily.
- [Prolactin Abnormality - Treatment](https://christopherlanetrust.org.uk/?elementor_library=prolactin-abnormality-3) - Treatment for Prolactin Abnormality Click here to view Diagnosing Prolactin Abnormality Treatment for excess prolactin (hyperprolactinemia) If your prolactin excess is caused by thyroid deficiency, your thyroid levels will be restored by thyroid replacement medicine and this will also cause your prolactin level to normalise. If your regular medicine is the reason for your high
- [Prolactin Abnormality - Diagnosis](https://christopherlanetrust.org.uk/?elementor_library=prolactin-abnormality-2) - Diagnosing Prolactin Abnormality Click here to view Treatment for Prolactin Abnormality Test The prolactin test is a simple blood test which should be taken 3-4 hours after waking. You do not need to make any special preparations beforehand. The normal ranges for prolactin in your blood are: Males: 2 to 18 nanograms per millilitre (ng/mL)
- [Arginine Vasopressin Deficiency - Diagnosis](https://christopherlanetrust.org.uk/?elementor_library=arginine-vasopressin-deficiency-2) - Diagnosing Arginine Vasopressin Deficiency (AVD) Click here to view Treatment for Arginine Vasopressin Deficiency (AVD) (Diabetes Insipidus) Testing An ADH test will help to diagnose diabetes insipidus, if your ADH level is low. High levels can indicate can help diagnose the syndrome of inappropriate diuretic hormone, or SIADH, a condition that occurs when the body
- [Thyroid Hormone Deficiency - Diagnosis](https://christopherlanetrust.org.uk/?elementor_library=thyroid-hormone-deficiency-2) - Diagnosing Thyroid Hormone Deficiency Click here to view Treatment for Thyroid Hormone Deficiency (Hypothyroidism) Tests Thyroid-stimulating hormone (TSH). TSH is made in the pituitary gland and controls the balance of thyroid hormones — including T4 and T3 — in your blood. This is usually the first test you will receive to check for thyroid hormone
- [Sex Hormone Deficiency - Diagnosis](https://christopherlanetrust.org.uk/?elementor_library=sex-hormone-deficiency-2) - Testing for Sex Hormone Deficiency Click here to view Treatment for Sex Hormone Deficiency (Secondary Hypogonadism) Your endocrinologist should test Estradiol/testosterone, sex hormone binding globulin (SHBG) early morning (usually 9am) and on more than one occasion Luteinising hormone, follicle stimulating hormone (LH/FSH). Prolactin – test on at least two occasions Men will be given a
- [Major Cause - Causes](https://christopherlanetrust.org.uk/?elementor_library=major-cause) - The Head Injury Connection Head injury survivors are not warned about common and potentially very serious after-effects which can occur at any time after injury even many years later. If you are depressed or impotent it could be because you suffered more than you realised from a head injury. Statement from Christopher Lane Trust In
- [Causes - Causes](https://christopherlanetrust.org.uk/?elementor_library=causes) - Head injury (major cause) – Read More • Brain surgery• Radiation treatment to the head or neck• Lack of blood flow to the brain or pituitary gland (stroke) or bleeding (hemorrhage) into the brain or pituitary gland• Certain medications, such as narcotics, high-dose corticosteroids such as prednisone, or certain cancer drugs called checkpoint inhibitors• Inflammation
- [4 Mistaken Reasons - Diagnosis](https://christopherlanetrust.org.uk/?elementor_library=4-mistaken-reasons) - FOUR MISTAKEN REASONS YOUR CONSULTANT MAY GIVE FOR REFUSING YOU A DYNAMIC TEST FOR GHD OR CORTISOL DEFICIENCY 1. “If the other pituitary hormones show no abnormality, there is no need to test for growth hormone deficiency.”There is much research demonstrating that growth hormone deficiency is the most common pituitary defect after traumatic brain injury,
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